Science Games For 3 Year Olds Chimeric antigen receptor CAR T cell therapies have transformed treatment of B cell malignancies However their broader application is limited by complex manufacturing
Science is the leading multidisciplinary international journal of peer reviewed research including analysis and news coverage of breakthroughs and policy Present vision restoration technologies have substantial constraints that limit their application in the clinical setting In this work we fabricated a subretinal nanoprosthesis using
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Integrating radiative and evaporative cooling shows promise for enhancing passive cooling but durable self curing integrated cooling paints remain underdeveloped We More than 3 billion years of evolution have produced an image of biology encoded into the space of natural proteins Here we show that language models trained at scale on
Toxic metal pollution is ubiquitous in soils yet its worldwide distribution is unknown We analyzed a global database of soil pollution by arsenic cadmium cobalt Colony stimulating factor 1 receptor CSF1R is primarily expressed in microglia Its monoallelic mutation causes CSF1R associated microgliopathy CAMP a major form of adult
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The CRL4CRBN E3 ubiquitin ligase is the target of molecular glue degrader compounds that reprogram ligase specificity to induce the degradation of clinically relevant neosubstrate Reactive oxygen species ROS function as key signals in plant adaptation to environmental stresses such as drought Roots respond to transient water unavailability by
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Chimeric antigen receptor CAR T cell therapies have transformed treatment of B cell malignancies However their broader application is limited by complex manufacturing

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Science is the leading multidisciplinary international journal of peer reviewed research including analysis and news coverage of breakthroughs and policy

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